Previously, we demonstrated a strong correlation between the amplitude of human speech and the emission rate of micron-scale expiratory aerosol particles, which are believed to play …
Protease-activated receptor-2 (PAR2) is involved in inflammatory responses and pain, therefore representing a promising therapeutic target for the treatment of immune-mediated …
The French phase 3 trial (OS 2006) testing zoledronic acid, an osteoclast inhibitor, with chemotherapy and surgery did not improve the outcome of patients with osteosarcoma (OS). To …
… named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).The first cluster of … 5,800,000 SARS-CoV-2-related deaths.Patients with cancer are more susceptible to SARS-…
… In 1906 patients for whom the SARCULATOR score could be calculated, 675 had a score equal or over 120, the 5-year OS was significantly worse compared to those with a …
G protein-coupled receptors (GPCRs) are involved in essentially all physiological processes in mammals. The classical GPCR signal transduction mechanism occurs by coupling to G …
… for the screening and identification of human SARS-CoV-2 seroconverters. … to help define previous exposure to SARS-CoV-2 in … SARS-CoV-1 and SARS-CoV-2—were used as controls. …
… A rationale SAR for the substitution pattern cannot be defined yet, and further substituents must be explored. However, it is possible to verify that possibly larger volume is tolerated in …
… The discovery and SAR of a new series of amino-acetonitrile derivatives (AAD) potent … To further explore the SAR, another series of compounds (25–36) with modifications of the R 2 …
… Developed by a surgeon who is a 54 former opera singer (co-author SAR) in partnership with the San Francisco Opera, the singing 55 mask here (Figure 1a,b; see Methods) uniquely …