Dysregulation of the complement system is evident in many CNS diseases but mechanisms regulating complement activation in the CNS remain unclear. In a recent large rat genome-…
… models indicated that the village of Darreh Shahniz, benefiting from rich natural … Tang-e-Tamradi, while the strongest indicator was “transportation infrastructure development” in Darreh …
Background Alzheimer’s disease (AD) is an age-related disease characterized by altered cognition, neuroinflammation, and neurodegeneration against which there is presently no …
Background: The positron emission tomography (PET) radiotracer Pittsburgh Compound-B (PIB) is an in vivo ligand for measuring β-amyloid (Aβ) load. Associations between PET PIB …
IntroductionOptimizing post-stroke rehabilitation strategies remains imperative for improving patient outcomes. Physical exercise, including outdoor walking, represents a promising …
The mountainous regions of Iran, particularly Chaharmahal and Bakhtiari Province, exhibit considerable potential for the development of geotourism. This study explores three main …
Apolipoprotein E ε4 allele (APOE ε4) increases the apolipoprotein E (apoE) protein levels in Alzheimer's disease (AD) cerebrospinal fluid (CSF). Thus, we hypothesized that apoE levels …
An important neurophathological hallmark of Alzheimer disease (AD) is the progressive formation of neurofibrillary tangles composed of aberrant hyperphosphorylated tau aggregates. …
… In this study, drinking and irrigation water quality in Shirin Darreh dam basin (1750 km2), NE Iran, was assessed. Thirtythree surface water, groundwater, and the reservoir water …