Neurotrophins acting through Trk signal-transducing receptors play essential roles in the nervous system, and probably in some non-neuronal tissues. In the present study, we used RT-…
Objective To analyze the HLA distribution in a population of individuals from Zambia in order to establish a possible relationship between the progression of human immunodeficiency …
HLA-B27 confers susceptibility to ankylosing spondylitis (AS) but the mechanism linking this association remains unknown. Other properties unrelated to its natural role of antigen …
Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease characterized by leukocyte infiltration into the central nervous system (CNS). Migration of lymphocyte …
HLA-B27 confers susceptibility to ankylosing spondylitis but AS disease mechanisms remain unknown. We determined here the effect of polymorphism and tapasin dependence on the …
Bone marrow has been considered the main source for isolation of multipotent mesenchymal stem cells for therapeutic approaches. However, alternative sources of mesenchymal stem …
Whereas it is nowadays clear that neurotrophins are involved in the regulation of various aspects of the functioning of immune system, knowledge of their actual immunomodulatory …
Background: Microparticles are present in low concentrations in normal plasma, but increase in several diseases including atherosclerosis, mainly through membrane activation …
C ellular activity of natural killer cells (NK cells) is defined by the balance between activat-ing and inhibitory signals coming from their receptors. With respect to this response, killer …
Rheumatoid arthritis (RA), a systemic autoimmune condition, causes joint damage and sometimes extraarticular lesions (cutaneous vasculitis, neuropathy, Felty’s syndrome, pericarditis…