Using a pharmacogenetic approach in 185 schizophrenics who have been prospectively assessed for clozapine response, we have examined the hypothesis that polymorphisms in the …
Current vitrimer technology uses only a handful of distinct reactions for cross-linking. New dynamic reactions can diversify vitrimer functionality and properties. In this paper, reversible …
The hydrolysis of cocaine and its N‐demethylated product, norcocaine, by esterases was examined in liver and serum. Both liver and serum enzymatically formed ecgonine methyl ester …
pharmrev.aspetjournals.org/article/S0031-6997(24)01338-3/abstractPharmacogenetics is a field of growing interest in medicine and within the pharmaceutical industry. To physicians whose patients do not respond to drug therapy as expected, …
The interaction of fifteen amphetamine analogs with the genetically polymorphic enzyme CYP2D6 was examined. All fourteen phenylisopropylamines tested were competitive inhibitors …
Micro-scale optical components play a crucial role in imaging and display technology, biosensing, beam shaping, optical switching, wavefront-analysis, and device miniaturization. …
The contracture produced by caffeine in isolated strips of human muscle was measured in normal specimens and in samples from three volunteers who had recovered from severe …
Hydrolysis of cocaine to ecgonine methyl ester in human plasma is mediated by cholinesterase. Cocaine hydrolysis by plasma is blocked by DFP and eserine and partially inhibited by …
Controlling the physical properties of soft materials with external stimuli enables researchers to mimic and study dynamic systems. Of particular interest are hydrogels, polymer networks …
Vitrimers are associative covalent adaptable networks that undergo reversible bond-exchange reactions while maintaining a fixed cross-linking density with changing temperature. To …