Given the anthropometric differences between men and women and previous evidence of sex-difference in genetic effects, we conducted a genome-wide search for sexually dimorphic …
A prospective study of 114 patients with DMD provided data for “power” calculations for future therapeutic trials. There was a decline in strength of 0.4 units per year (on a 0‐10 scale). …
Tamoxifen is biotransformed by CYP2D6 to 4‐hydroxytamoxifen and 4‐hydroxy N‐desmethyl tamoxifen (endoxifen), both with greater antiestrogenic potency than the parent drug. …
As one of the Law-Professors at the University of London, I planned and partly delivered a syste-matical Course of Lectures on General or Abstract Jurisprudence. In the ten lectures …
A major challenge in genome‐wide association studies (GWASs) is to derive the multiple testing threshold when hypothesis tests are conducted using a large number of single …
Human longevity is heritable, but genome-wide association (GWA) studies have had limited success. Here, we perform two meta-analyses of GWA studies of a rigorous longevity …
Background— Coronary artery calcification (CAC) detected by computed tomography is a noninvasive measure of coronary atherosclerosis, which underlies most cases of myocardial …
Detailed medical family history data have been proposed to be effective in identifying high-risk families for targeted intervention. With use of a validated and standardized quantitative …
… This study aims to reveal the spatio-temporal patterns of TB in the Qinghai province, which could be helpful in the planning and implementing key preventative measures. …
… recent field-based research in the Copperbelt province of Zambia, a region where the practice of … centres and experiences in the Copperbelt province could inform policy and practice in …