N 6 -methyladenosine (m 6 A) on mRNAs is critical for various biological processes, yet whether m 6 A regulates drug resistance remains unknown. Here we show that developing …
The intrinsic properties of distinct types of neuron play important roles in cortical network dynamics. One crucial determinant of neuronal behaviour is the cell's response to rhythmic …
Carbon dioxide capture and sequestration is drawing increasing attention as a potential method for controlling greenhouse gas emissions. Low cost ionic liquid analogues, namely, …
We use a new panel dataset to study the network of formal firm linkages within and across 52 aerospace clusters in North America and Europe. Our theoretical framework, built upon the …
Kenya was where the term" informal sector" was first used in 1971. During the 1980s the term" jua kali"--in Swahili" hot sun"--came to be used of the informal sector artisans, such as …
Background Hypomethylating drugs are the standard treatment for patients with high-risk myelodysplastic syndromes. Survival is poor after failure of these drugs; there is no approved …
We conducted a phase I clinical trial of H3B-8800, an oral small molecule that binds Splicing Factor 3B1 (SF3B1), in patients with MDS, CMML, or AML. Among 84 enrolled patients (42 …
From its early stages, design-based research (DBR) has had the vision of developing into a design science of education (Collins, 1992), in which critical elements in learning …
How do the number of trade partners and the concentration of trade among partners affect the economic growth of a country? We refer to these characteristics as the structure of trade, …