dmd.aspetjournals.org/article/S0090-9556(25)06689-9/abstractThe microsomal metabolism of caffeine and its primary dimethylxanthine metabolites, paraxanthine, theophylline, and theobromine, was investigated in 15 different human livers, …
The traditional concern of pharmacogenetics was Mendelian (monogenic) variation, which visibly affected some drug responses. Pharmacogenetics was broadened by the observation …
Convenient strategies for the deconstruction and reprocessing of thermosets could improve the circularity of these materials, but most approaches developed to date do not involve …
… Address requests for reprints to: Werner Kalow, MD, Professor, Department of Pharmacology, University of Toronto, 1 King’s College Circle, Medical Sciences Building …
Objectives Safe and effective care after discharge requires parental education in the pediatric emergency department (ED). Parent-provider communication may be more difficult with …
Introduction Emergency department (ED) visits related to opioid use disorder (OUD) have increased nearly twofold over the last decade. Treatment with buprenorphine has been …
Importance Screening for adverse social determinants of health (SDOH) in the emergency department (ED) may help reduce health disparities in underserved populations. Objective To …
A method is presented for the use of caffeine, in the forms commonly ingested by a large proportion of the world's population, to test for the clinically important acetylation polymorphism. …
Importance Emergency department (ED) triage substantially affects how long patients wait for care but triage scoring relies on few objective criteria. Prior studies suggest that Black and …
The composition of low-T g n-butylacrylate-block-(acetoxyaceto)ethyl acrylate block polymers is investigated as a strategy to tune the properties of dynamically cross-linked vinylogous …