Background Glucocorticoid treatment is recommended as a standard of care in Duchenne muscular dystrophy; however, few studies have assessed the long-term benefits of this …
The learning environment comprises the psychological, social, cultural and physical setting in which learning occurs and has an influence on student motivation and success. The …
Heart disease is often the end result of inherited genetic defects, which may potentially be treatable using a gene-transfer approach. Recombinant adeno-associated virus (rAAV)-…
Background Duchenne muscular dystrophy (DMD) is a severe, progressive, and rare neuromuscular, X-linked recessive disease. Dystrophin deficiency is the underlying cause of …
One of the most significant historiographical developments of the last decade has been the revival of an early work by Jürgen Habermas, his Strukturwandel der Offentlichkeit, translated …
The deep population history of East Asia remains poorly understood owing to a lack of ancient DNA data and sparse sampling of present-day people 1 , 2 . Here we report genome-wide …
With the reduction of solid oxide fuel cells (SOFCs) operating temperature to the range of 600 C–800 C, metallic alloy with high oxidation resistance are used to replace traditional …
The canonical Wnt/β-catenin signalling pathway governs diverse developmental, homeostatic and pathological processes. Palmitoylated Wnt ligands engage cell-surface frizzled (FZD) …
Human enteroids—epithelial spheroids derived from primary gastrointestinal tissue—are a promising model to study pathogen-epithelial interactions. However, accessing the apical …
Background The senses of touch and proprioception evoke a range of perceptions and rely on the ability to detect and transduce mechanical force. The molecular and neural …