Protein modification by strain-promoted alkyne–nitrone cycloaddition
Method A: The rate constant was determined by 1 H NMR spectroscopy in CD 3 CN/D 2 O (3: 1);[2 a]= 18 mm,[4 a–f]= 16.4 m m. Method B: The rate constant was determined 18 by UV …
Method A: The rate constant was determined by 1 H NMR spectroscopy in CD 3 CN/D 2 O (3: 1);[2 a]= 18 mm,[4 a–f]= 16.4 m m. Method B: The rate constant was determined 18 by UV …
There is currently a lack of effective drugs to treat people infected with SARS-CoV-2, the cause of the global COVID-19 pandemic. The SARS-CoV-2 Non-structural protein 13 (NSP13) …
ALTHOUGH CURABLE, TB frequently leaves the individual with chronic physical and psycho-social impairment, but these consequences have been largely neglected. The 1st …
We study the dynamics of an atomic quantum dot, ie, a single atom in a tight optical trap which is coupled to a superfluid reservoir via laser transitions. Quantum interference between …
Direct comparison of the hepatoma cell lines HepG2 and HepaRG has previously been performed by only evaluating a limited set of genes or proteins. In this study, we examined the …
To fight bone diseases characterized by poor bone quality like osteoporosis and osteoarthritis, as well as in reconstructive surgery, there is a need for a new generation of implantable …
The Kondo effect in quantum dots (QDs)—artificial magnetic impurities—attached to ferromagnetic leads is studied with the numerical renormalization group method. It is shown that the …
Research into the chemical biology of bromodomains has been driven by the development of acetyl-lysine mimetics. The ligands are typically anchored by binding to a highly conserved …
Executives and scholars alike strongly emphasize the increasing need to adequately respond to the economic needs of customers while simultaneously considering human welfare and …
RNA methylation is emerging as a regulatory RNA modification that could have important roles in the control and coordination of gene transcription and protein translation. Herein, we …