Several lines of work have shown that astrocytes release glutamate in response to receptor activation, which results in a modulation of local synaptic activity. Astrocytic glutamate …
Canavan's disease (CD) is a fatal, hereditary disorder of CNS development that has been linked to mutations in the gene for the enzyme aspartoacylase (ASPA) (EC 3.5.1.15). ASPA …
Worldwide HIV-1 vaccine efforts are guided by the principle that HIV-specific T cell responses may provide protection from infection or delay overt disease. However, no clear correlates …
Psoriasis vulgaris, a skin disease that is considered to be the result of a type 1 autoimmune response, provides an opportunity for studying the changes that occur in a target-diseased …
… I formed my first favorable impression of this book on turning the title page and coming upon a passage from Psalms (102:25-27), which at once puts the whole realm of the physics of …
Background—Vascular calcification is an ectopic calcification that commonly occurs in atherosclerosis. Because tumor necrosis factor-α (TNF-α), a pleiotropic cytokine found in …
… (PAGE) apparatus. Rat canalicular membrane vesicles (CMVs) (50 pg) and Gpl70 purified from Chinese hamster ovary cells were used as positive controls. SDS PAGE was performed …
Background—The pulmonary veins (PVs) and surrounding ostial areas frequently house focal triggers or reentrant circuits critical to the genesis of atrial fibrillation (AF). We developed …
Background—This study was performed to compare implantation of a DDI pacemaker with rate hysteresis with no implant in respect to syncopal recurrences in patients with severe …
… The "Finale" of the ballet makes this point explicitly, beginning with the narrator's remark that Lenox Avenue's passersby simultaneously hear the religious music of salvationseekers and …