Objective The Vitamin D receptor (VDR) has been positively associated with skeletal muscle mass, function and regeneration. Mechanistic studies have focused on the loss of the …
The opioid system plays a critical role in both the experience and management of pain. Although acute activation of the opioid system can lead to pain relief, the effects of chronic pain …
New Findings What is the central question of this study? Is electrical pulse stimulation (EPS) an in vitro exercise model able to elicit the hypertrophy of human muscle cells? What is the …
Background The andropause is associated with declines in serum testosterone (T), loss of muscle mass (sarcopenia), and frailty. Two major interventions purported to offset sarcopenia …
Key points Reduced vitamin D receptor (VDR) expression prompts skeletal muscle atrophy. Atrophy occurs through catabolic processes, namely the induction of autophagy, while …
Background & aims The skeletal muscle anabolic effects of n-3 polyunsaturated fatty acids (n-3 PUFA) appear favoured towards women; a property that could be exploited in older …
Aerobic exercise improves outcomes in a variety of chronic health conditions, yet the support for exercise-induced effects on chronic pain in humans is mixed. Although many rodent …
The excavation was located in the center of Moshav Tarum (Fig 1), after the discovery of a large potsherd and flint scattering in archaeological inspections. A probe trench revealed a …
Background Sarcopenia is an age‐related muscle disease that increases the risk of falls, disabilities, and death. It is associated with increased muscle protein degradation driven by …
Ageing limits growth capacity of skeletal muscle (eg in response to resistance exercise), but the role of satellite cell (SC) function in driving this phenomenon is poorly defined. Younger (…